Reduced vitamin D levels in painful diabetic peripheral neuropathy

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The relationship between serum vitamin D and vitamin B12 levels and diabetic peripheral neuropathy

Abstract Objective: Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes. Beside the known factors such as hyperglycemia in the pathogenesis of this complication, other etiologies may play role in the pathogenesis of this complication. The aim of this study was the evaluation of the role of serum vitamin D and vitamin B12 levels in this process. Material a...

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Vitamin D for the treatment of painful diabetic neuropathy.

OBJECTIVE To assess the effect of high-dose vitamin D in patients with painful diabetic neuropathy. METHODS A single intramuscular dose of 600 000 IU vitamin D was administered, and the effects on metabolic parameters and neuropathic pain assessed over 20 weeks. RESULTS 143 participants with predominantly type 2 diabetes, aged 52.31±11.48 years, with a Douleur Neuropathique 4 (DN4) score (3...

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the relationship between serum vitamin d and vitamin b12 levels and diabetic peripheral neuropathy

abstract objective: diabetic peripheral neuropathy (dpn) is one of the most common complications of diabetes. beside the known factors such as hyperglycemia in the pathogenesis of this complication, other etiologies may play role in the pathogenesis of this complication. the aim of this study was the evaluation of the role of serum vitamin d and vitamin b12 levels in this process. material and ...

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Treating Painful Diabetic Peripheral Neuropathy: An Update.

Painful diabetic peripheral neuropathy occurs in approximately 25% of patients with diabetes mellitus who are treated in the office setting and significantly affects quality of life. It typically causes burning pain, paresthesias, and numbness in a stocking-glove pattern that progresses proximally from the feet and hands. Clinicians should carefully consider the patient's goals and functional s...

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Venlafaxine HCl in the treatment of painful peripheral diabetic neuropathy.

In a recent letter by Davis and Smith (1), venlafaxine HCl was reported to be effective in the symptomatic treatment of patients with painful diabetic neuropathy. This observation is in accordance with a similar finding made by us. We administered venlafaxine HCl in 8 patients who had unremitting painful peripheral diabetic neuropathy that did not respond to conventional analgesia. All patients...

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ژورنال

عنوان ژورنال: Diabetic Medicine

سال: 2018

ISSN: 0742-3071

DOI: 10.1111/dme.13798